Permeation of Pharmaceutical Compounds Through Silanized Poly(dimethylsiloxane)

Effect of plasma surface treatment of poly(dimethylsiloxane) on the permeation of pharmaceutical compounds

This paper addresses the modification of poly(dimethylsiloxane), i.e. PDMS, using plasma surface treatment and a novel application of the membrane created. A set of model compounds were analysed to determine their permeation through PDMS, both with and without plasma treatment. It was found that plasma treatment reduced permeation for the majority of compounds but had little effect on some comp...

Permeation through cornea.

The permeability of the cornea to drugs is clinically important because it is the major factor determining the efficacy of topically applied ophthalmic preparations. With this perspective, the present article gives a brief update and overview of corneal structure and proposed mechanisms of permeation. Physiological, physicochemical and formulation factors affecting drug permeation through corne...

Effect of polydimethylsiloxane surfaces silanized with different nitrogen-containing groups on the adhesion progress of epithelial cells

Plasma Technology for Removal of Pharmaceutical Compounds from the Environment

Pharmaceutical Compounds in the Environment